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Research that shows how the immune system could be more effective

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An elevated body temperature can kill. Yet fever?which is precisely that?is a common response to infection. Recent research shows how febrile temperatures encourage a particular protein called Hsp90 to shepherd immune-system cells to sites of infection. This research suggests ways in which the process might be regulated to a patient?s advantage. Drugs that increase Hsp90 production should promote the migration of T-cells to lymph nodes, and so aid the treatment of infections that need a larger immune response. Conversely, drugs that diminish Hsp90 production might help reduce T-cell movement in people with so-called auto-immune disorders, such as multiple sclerosis and rheumatoid arthritis, in which immune-system cells attack the body they are part of. www.economist.com/science-and-technology/2019/01/15/how-fever-helps-combat-disease-has-now-been-better-understood
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By oliver

16 January 2019

 
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